{"id":1641,"date":"2026-09-22T12:45:12","date_gmt":"2026-09-22T12:45:12","guid":{"rendered":"https:\/\/koldaweb.com\/?p=1641"},"modified":"2026-09-22T12:45:15","modified_gmt":"2026-09-22T12:45:15","slug":"rdc-lessai-clinique-du-vaccin-ervebo-demarre-en-ituri-contre-ebola","status":"publish","type":"post","link":"https:\/\/koldaweb.com\/index.php\/2026\/09\/22\/rdc-lessai-clinique-du-vaccin-ervebo-demarre-en-ituri-contre-ebola\/","title":{"rendered":"RDC : l\u2019essai clinique du vaccin Ervebo d\u00e9marre en Ituri contre Ebola"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\"><strong>\u00c0 Bunia, les premiers agents de sant\u00e9 ont re\u00e7u le vaccin dans le cadre d\u2019une \u00e9tude destin\u00e9e \u00e0 mesurer son \u00e9ventuelle protection contre la souche Bundibugyo<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Une nouvelle \u00e9tape est franchie dans la riposte contre l\u2019\u00e9pid\u00e9mie d\u2019Ebola en <strong>R\u00e9publique d\u00e9mocratique du Congo<\/strong>. Les premiers professionnels de sant\u00e9 et autres travailleurs de premi\u00e8re ligne ont re\u00e7u, le <strong>19 septembre 2026 \u00e0 Bunia<\/strong>, en Ituri, le vaccin <strong>Ervebo<\/strong>, dans le cadre d\u2019un essai clinique. L\u2019objectif est de d\u00e9terminer si ce vaccin, d\u00e9j\u00e0 utilis\u00e9 contre la souche Za\u00efre, peut \u00e9galement offrir une protection contre la souche <strong>Bundibugyo<\/strong>, responsable de l\u2019\u00e9pid\u00e9mie actuelle.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>20 000 volontaires cibl\u00e9s<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">L\u2019\u00e9tude, men\u00e9e avec la participation des autorit\u00e9s sanitaires congolaises, de l\u2019OMS, d\u2019Africa CDC et de M\u00e9decins sans fronti\u00e8res, doit concerner environ <strong>20 000 personnes<\/strong> parmi les personnels les plus expos\u00e9s : m\u00e9decins, infirmiers, agents de sant\u00e9 et travailleurs intervenant dans la d\u00e9sinfection notamment. Le suivi est pr\u00e9vu sur une p\u00e9riode de <strong>neuf \u00e0 douze mois<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">L\u2019enjeu scientifique est important : <strong>Ervebo est homologu\u00e9 contre le virus Ebola de la souche Za\u00efre<\/strong>, mais son niveau de protection contre Bundibugyo n\u2019est pas encore \u00e9tabli chez l\u2019\u00eatre humain. Des donn\u00e9es pr\u00e9liminaires laissent envisager une \u00e9ventuelle protection crois\u00e9e, mais l\u2019essai doit pr\u00e9cis\u00e9ment permettre de mesurer cette efficacit\u00e9.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>70 000 doses mises \u00e0 disposition<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">En ao\u00fbt, le Groupe international de coordination pour l\u2019approvisionnement en vaccins avait annonc\u00e9 la mise \u00e0 disposition de <strong>70 000 doses d\u2019Ervebo<\/strong> pour la RDC. Selon l\u2019OMS, <strong>20 000 doses<\/strong> sont destin\u00e9es \u00e0 l\u2019essai clinique de phase III, tandis que <strong>50 000 doses<\/strong> sont r\u00e9serv\u00e9es aux personnels de sant\u00e9 et aux intervenants de premi\u00e8re ligne, conform\u00e9ment aux recommandations en vigueur.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">La vaccination avait d\u00e9j\u00e0 commenc\u00e9 dans d\u2019autres provinces dans le cadre de l\u2019\u00e9tude, notamment en <strong>Tshopo et au Bas-U\u00e9l\u00e9<\/strong>, avant son lancement en Ituri.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Une \u00e9pid\u00e9mie toujours pr\u00e9occupante<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">L\u2019Ituri reste l\u2019\u00e9picentre de l\u2019\u00e9pid\u00e9mie actuelle. Selon le bilan de l\u2019Institut national de sant\u00e9 publique congolais cit\u00e9 par l\u2019AFP, au <strong>19 septembre 2026<\/strong>, l\u2019\u00e9pid\u00e9mie avait fait <strong>7 541 cas et 3 639 d\u00e9c\u00e8s<\/strong>, avec une pr\u00e9sence du virus signal\u00e9e dans sept provinces.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Africa CDC a toutefois indiqu\u00e9 que le nombre de cas semblait atteindre un plateau, tout en soulignant que l\u2019\u00e9pid\u00e9mie ne pouvait pas encore \u00eatre consid\u00e9r\u00e9e comme ma\u00eetris\u00e9e. Les d\u00e9placements difficiles, la pr\u00e9sence de groupes arm\u00e9s et la d\u00e9fiance d\u2019une partie de la population compliquent notamment la riposte sanitaire.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pour les chercheurs et les autorit\u00e9s sanitaires, l\u2019essai Ervebo constitue donc une \u00e9tape destin\u00e9e \u00e0 <strong>apporter des donn\u00e9es scientifiques sur une \u00e9ventuelle protection contre la souche Bundibugyo<\/strong>. Les r\u00e9sultats devront permettre de mieux orienter les strat\u00e9gies de vaccination face \u00e0 cette \u00e9pid\u00e9mie.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">La R\u00e9daction Koldaweb.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00c0 Bunia, les premiers agents de sant\u00e9 ont re\u00e7u le vaccin dans le cadre d\u2019une&#8230;<\/p>\n","protected":false},"author":3,"featured_media":1636,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_joinchat":[],"footnotes":""},"categories":[3],"tags":[490,123,489],"class_list":["post-1641","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sante","tag-ebola","tag-rdc","tag-vaccin"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>RDC : l\u2019essai clinique du vaccin Ervebo d\u00e9marre en Ituri contre Ebola -<\/title>\n<meta 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